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. 2012:5:55-8.
doi: 10.1016/j.rmedc.2011.08.005. Epub 2011 Oct 5.

Fibrinolytic therapy for parapneumonic empyema during pregnancy

Hakki Ulutas  1 , Erdal Yekeler  2 , Zafer Hasan Ali Sak  3 , Ihsan Doru  4 , Akin Kuzucu  1
Affiliations

Fibrinolytic therapy for parapneumonic empyema during pregnancy

Hakki Ulutas et al. Respir Med Case Rep. 2012.

Abstract

Pneumonia and parapneumonic complicated effusion during pregnancy is uncommon but poses potentially serious risks to both mother and fetus. Enzymatic debridement of the pleural cavity with fibrinolytic agents is a noninvasive option that can facilitate drainage and prevent the need for surgery. Herein, we describe the cases of two pregnant women with parapneumonic empyema who were successfully treated with intrapleural fibrinolytic therapy.

Keywords: Intrapleural fibrinolytic therapy; Parapneumonic empyema; Pregnancy.

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Figures

Fig. 1
Fig. 1
Chest radiography of patient at presentation.
Fig. 2
Fig. 2
Computed tomography of the chest showing large left pleural effusion and pneumothorax.
Fig. 3
Fig. 3
a,b. Chest radiography of patient after treatment of intrapleural streptokinase.
Fig. 4
Fig. 4
a. Chest radiography of patient at presentation; b. Chest radiography of patient after tube thoracostomy.
Fig. 5
Fig. 5
a,b. Thoracic magnetic resonance imaging showing elevation of the diaphragm, loculated pleural fluid and atelectasis.
Fig. 6
Fig. 6
Chest radiography of patient after treatment of intrapleural streptokinase.
See this image and copyright information in PMC

References

    1. Bouros D., Tzouvelekis A., Antoniou K.M., Heffner J.E. Intrapleural fibrinolytic therapy for pleural infection. Pulm Pharmacol Ther. 2007;20:616–626. - PubMed
    1. Goodnight W.H., Soper D.E. Pneumonia in pregnancy. Crit Care Med. 2005;33(Suppl):390–397. - PubMed
    1. Maskell N.A., Christopher W.H., Davies M.D. Controlled trial of intrapleural streptokinase for pleural infection. N Eng J Med. 2005;352:865–874. - PubMed
    1. Tokuda Y., Matsushima D., Stein G.H., Miyagi S. Intrapleural fibrinolytic agents for empyema and complicated parapneumonic effusions. Chest. 2006;129:783–790. - PubMed
    1. Misthos P., Sepsas E., Konstantinou M., Athanassiadi K., Skottis I., Lioulias A. Early use of intrapleural fibrinolytics in management of postpneumonic empyema. A prospective study. Eur J Cardiothorac Surg. 2005;28:599–603. - PubMed