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Case Reports
. 2015 Jun 10:9:137.
doi: 10.1186/s13256-015-0613-9.

Neuromyelitis optica with linear enhancement of corpus callosum in brain magnetic resonance imaging with contrast: a case report

Mohammad Ali Sahraian  1 , Abdorreza Naser Moghadasi  2 , Mahsa Owji  3 , Hoda Naghshineh  4 , Alireza Minagar  5
Affiliations
Case Reports

Neuromyelitis optica with linear enhancement of corpus callosum in brain magnetic resonance imaging with contrast: a case report

Mohammad Ali Sahraian et al. J Med Case Rep. .

Abstract

Introduction: Neuromyelitis optica is a demyelinating disease of the central nervous system with various patterns of brain lesions. Corpus callosum may be involved in both multiple sclerosis and neuromyelitis optica. Previous case reports have demonstrated that callosal lesions in neuromyelitis optica are usually large and edematous and have a heterogeneous intensity showing a "marbled pattern" in the acute phase. Their size and intensity may reduce with time or disappear in the chronic stages.

Case presentation: In this report, we describe a case of a 25-year-old Caucasian man with neuromyelitis optica who presented clinically with optic neuritis and myelitis. His brain magnetic resonance imaging demonstrated linear enhancement of the corpus callosum. Brain images with contrast agent added also showed linear ependymal layer enhancement of the lateral ventricles, which has been reported in this disease previously.

Conclusions: Linear enhancement of corpus callosum in magnetic resonance imaging with contrast agent could help in diagnosing neuromyelitis optica and differentiating it from other demyelinating disease, especially multiple sclerosis.

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Figures

Fig. 1
Fig. 1
T2-weighted and T1-weighted images with contrast agent. a,b Images show involvement of the corpus callosum with linear enhancement. c,d Thin ependymal enhancement of lateral ventricular surfaces (pencil-thin ependymal enhancement)
Fig. 2
Fig. 2
Axial fluid-attenuated inversion recovery magnetic resonance image of the patient shows hyperintense lesions around the ventricles and corpus callosum
See this image and copyright information in PMC

References

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