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Review
. 2015:2015:258589.
doi: 10.1155/2015/258589. Epub 2015 May 7.

Complementary and Alternative Therapies for Autism Spectrum Disorder

Affiliations
Review

Complementary and Alternative Therapies for Autism Spectrum Disorder

Natascia Brondino et al. Evid Based Complement Alternat Med. 2015.

Abstract

Background. Complementary and alternative medicine (CAM) represents a popular therapeutic option for patients with autism spectrum disorder (ASD). Unfortunately, there is a paucity of data regarding the efficacy of CAM in ASD. The aim of the present systematic review is to investigate trials of CAM in ASD. Material and Methods. We searched the following databases: MEDLINE, EMBASE, Cochrane Database of Systematic Reviews, CINAHL, Psychology and Behavioral Sciences Collection, Agricola, and Food Science Source. Results. Our literature search identified 2687 clinical publications. After the title/abstract screening, 139 publications were obtained for detailed evaluation. After detailed evaluation 67 studies were included, from hand search of references we retrieved 13 additional studies for a total of 80. Conclusion. There is no conclusive evidence supporting the efficacy of CAM therapies in ASD. Promising results are reported for music therapy, sensory integration therapy, acupuncture, and massage.

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References

    1. Blenner S., Augustyn M. Is the prevalence of autism increasing in the United States? The British Medical Journal. 2014;348 doi: 10.1136/bmj.g3088.g3088 - DOI - PubMed
    1. Baron-Cohen S., Scott F. J., Allison C., et al. Prevalence of autism-spectrum conditions: UK school-based population study. British Journal of Psychiatry. 2009;194(6):500–509. doi: 10.1192/bjp.bp.108.059345. - DOI - PubMed
    1. Watts T. J. The pathogenesis of autism. Clinical Medicine Insights: Pathology. 2008;1:99–103. - PMC - PubMed
    1. Tonge B. J., Bull K., Brereton A., Wilson R. A review of evidence-based early intervention for behavioural problems in children with autism spectrum disorder: the core components of effective programs, child-focused interventions and comprehensive treatment models. Current Opinion in Psychiatry. 2014;27(2):158–165. doi: 10.1097/yco.0000000000000043. - DOI - PubMed
    1. Mohammadi M.-R., Yadegari N., Hassanzadeh E., et al. Double-blind, placebo-controlled trial of risperidone plus amantadine in children with autism: a 10-week randomized study. Clinical Neuropharmacology. 2013;36(6):179–184. doi: 10.1097/wnf.0b013e3182a9339d. - DOI - PubMed

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