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Comment
. 2015 Jul;135(7):1713-1714.
doi: 10.1038/jid.2015.92.

A New View of Vitiligo: Looking at Normal-Appearing Skin

Mauro Picardo  1 , Emanuela Bastonini  2
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Free article
Comment

A New View of Vitiligo: Looking at Normal-Appearing Skin

Mauro Picardo et al. J Invest Dermatol. 2015 Jul.
Free article

Abstract

Debate over the pathogenesis of vitiligo is still ongoing among scientists, with several hypotheses currently under consideration. The study by Wagner et al. in this issue focuses on the role of E-cadherin-mediated cell adhesion in vitiliginous epidermis under oxidative and mechanical stress. Their work highlights how alterations in cell-cell adhesion across nonlesional melanocyte membranes in patients with vitiligo argue for primary intrinsic defects in the melanocytes.

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References

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