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. 2015 Jun 12:2015:0306.

Urinary tract infection in children: recurrent infections

James Larcombe  1
Affiliations

Urinary tract infection in children: recurrent infections

James Larcombe. BMJ Clin Evid. .

Abstract

Introduction: Up to 11% of girls and 7% of boys will have had a urinary tract infection (UTI) by the age of 16 years, and recurrence of infection is common. Vesicoureteric reflux (VUR) is identified in up to 40% of children being investigated for a first UTI, and is a risk factor for, but weak predictor of, renal parenchymal defects.

Methods and outcomes: We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of prophylactic antibiotics to prevent recurrent urinary tract infection in children? We searched: Medline, Embase, The Cochrane Library, and other important databases up to December 2013 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review).

Results: We found three studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.

Conclusions: In this systematic review we present information relating to the effectiveness and safety of the following intervention: prophylactic antibiotics.

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References

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