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Case Reports
. 2015 Jun;140(12):913-6.
doi: 10.1055/s-0041-102040. Epub 2015 Jun 12.

[Imported histoplasmosis]

[Article in German]
Affiliations
Case Reports

[Imported histoplasmosis]

[Article in German]
Katarina Stete et al. Dtsch Med Wochenschr. 2015 Jun.

Abstract

Infections with Histoplasma capsulatum are rare in Germany, and mostly imported from endemic areas. Infections can present as localized or disseminated diseases in immunocompromised as well as immunocompetent hosts. A travel history may be a major clue for diagnosing histoplasmosis. Diagnostic tools include histology, cultural and molecular detection as well as serology. Here we present four cases of patients diagnosed and treated in Freiburg between 2004 and 2013 that demonstrate the broad range of clinical manifestations of histoplasmosis: an immunocompetent patient with chronic basal meningitis; a patient with HIV infection and fatal disseminated disease; a patient with pulmonary and cutaneous disease and mediastinal and cervical lymphadenopathy; and an immunosuppressed patient with disseminated involvement of lung, bone marrow and adrenal glands.

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