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Case Reports
. 2015 Jul 14;85(2):197-8.
doi: 10.1212/WNL.0000000000001726. Epub 2015 Jun 12.

Clinical and radiologic reversal of stroke-like episodes in MELAS with high-dose L-arginine

Ishita Siddiq  1 , Elysa Widjaja  1 , Ingrid Tein  2
Affiliations
Case Reports

Clinical and radiologic reversal of stroke-like episodes in MELAS with high-dose L-arginine

Ishita Siddiq et al. Neurology. .
No abstract available

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Figures

Figure
Figure. Brain MRI at time of clinical presentations and after l-arginine treatment
(A) MRI showing normal basal ganglia, left superior temporal gyrus high FLAIR signal, and (B) left parietal lobe high FLAIR signal with effacement of sulci. (C) New abnormal signal in bilateral basal ganglia, as well as right occipital pole, and (D) improvement of the left parietal lobe lesion. (E) New lesion of the right pons. (F) MRI repeated after l-arginine treatment showing resolution of the right pontine lesion, but the basal ganglia, right occipital pole, and left superior temporal gyrus lesions remained unchanged (not shown). (G) Magnetic resonance spectroscopy (baseline subtracted in light green and nonbaseline subtracted in yellow) shows high lactate doublet peak at a chemical shift of 1.33 ppm acquired from left basal ganglia. FLAIR = fluid-attenuated inversion recovery.
See this image and copyright information in PMC

References

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