Copeptin in acute coronary syndromes and heart failure management: State of the art and future directions

Abstract

Over the past two decades, the use of multiple biomarkers has changed cardiovascular disease management. Recently, several trials have assessed the diagnostic and prognostic performances of copeptin, especially in patients with heart failure or acute coronary syndromes. Primary results are interesting, with copeptin looking promising for: the management of patients who present at emergency departments early after chest pain onset and the risk stratification of patients with heart failure. The purpose of this article is to review the data on the place of copeptin in the management of patients with chest pain or heart failure.

Keywords: Acute coronary syndromes; Chest pain; Copeptin; Copeptine; Coronaropathie; Coronary artery disease; Douleur thoracique; Heart failure; Insuffisance cardiaque; Syndrome coronaire aigu.