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. 2015:2015:809492.
doi: 10.1155/2015/809492. Epub 2015 May 14.

Caloric Restriction Effect on Proinflammatory Cytokines, Growth Hormone, and Steroid Hormone Concentrations during Exercise in Judokas

Salma Abedelmalek  1 , Hamdi Chtourou  2 , Nizar Souissi  2 , Zouhair Tabka  1
Affiliations

Caloric Restriction Effect on Proinflammatory Cytokines, Growth Hormone, and Steroid Hormone Concentrations during Exercise in Judokas

Salma Abedelmalek et al. Oxid Med Cell Longev. 2015.

Abstract

The aim of this study was to evaluate the effect of caloric restriction on the immune and hormonal responses during exercise in judo athletes. In a randomised order, 11 male judokas (age: 20.45 ± 0.51; height: 1.71 ± 0.3 m; and body weight: 75.9 ± 3.1 kg) participate in this study during a period of weight maintenance (baseline) and after 7 days of caloric restriction (CR). All subjects performed the Special Judo Fitness Test (SJFT) during the two conditions. Values for nutrient intakes were obtained from a 7 d food record kept during a period of weight maintenance and after a 7-day food restriction (-5~6 MJ/day). Our results showed that CR resulted in significant decreases in body weight (P < 0.05) and performance (P < 0.05). However, heart rate and SJFT index (P < 0.05) increase significantly during CR in comparison to baseline. Moreover, exercise leads to a significant increase in testosterone, cortisol, growth hormone (GH), leukocytes, neutrophils, TNF-α, and IL-6, in both CR and baseline conditions. Compared to baseline, TNF-α and IL-6 were significantly higher during CR condition (P < 0.05). Additionally, CR leads to an increase in cortisol and GH (P < 0.05) and a decrease in testosterone concentrations (P < 0.05).

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Figures

Figure 1
Figure 1
Growth hormone (GH) (a), testosterone (b), and cortisol (c) concentrations (ng·mL−1) measured before the exercise (P1) and immediately (P2) and 60 min after (P3) the exercise during baseline and caloric restriction (CR) conditions. All values are expressed as mean (±SD). ∗ indicates significant difference with (P1) during the same condition; ¶ indicates significant difference in comparison with baseline (P < 0.05).
Figure 2
Figure 2
Plasma concentrations (pg/mL) of interleukin-6 (IL-6) (a) and TNF-α (b) measured before (P1) and immediately (P2) and 60 min after (P3) the exercise during baseline and caloric restriction (CR) conditions. All values are expressed as mean (±SD). ∗ indicates significant difference with (P1) during the same condition; ¶ indicates significant difference in comparison with baseline (P < 0.05).
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