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Case Reports
. 2014 Oct 1:11:4-6.
doi: 10.1016/j.gore.2014.07.002. eCollection 2015 Jan.

Primary osteosarcoma of the uterus with cardiac and pulmonary metastases

Cynthia Abraham  1 , Roisin O'Cearbhaill  2 , Robert Soslow  2
Affiliations
Case Reports

Primary osteosarcoma of the uterus with cardiac and pulmonary metastases

Cynthia Abraham et al. Gynecol Oncol Rep. .

Abstract

•This is the first reported case describing a female with primary uterine osteosarcoma that exhibited cardiac and pulmonary metastases.•Although extremely rare, uterine osteosarcomas, like leiomyosarcomas, do respond to doxorubicin and ifosfamide.•Uterine osteosarcoma behaves aggressively and is associated with a poor prognosis.

Keywords: Cardiac metastasis; Pulmonary metastasis; Uterine osteosarcoma.

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Figures

Fig. 1
Fig. 1
Entire gross specimen bivalved.
Fig. 2
Fig. 2
a. Osteoclast-like giant cells and pleomorphic tumor cells are distributed within prominent eosinophilic matrix (osteoid). b. The osteoid is focally calcified, imparting the appearance of bone.
See this image and copyright information in PMC

References

    1. Carleton C.C., Williamson J.W. Osteogenic sarcoma of the uterus. Arch. Pathol. 1961;72:135–139. - PubMed
    1. D'Angelo E., Prat J. Uterine sarcomas: a review. Gynecol. Oncol. 2010;116(1):131–139. (Jan) - PubMed
    1. DiSaia, Creasman . 8th ed. 2012. Sarcoma of the Uterus in Clinical Gynecologic Oncology; pp. 175–187.
    1. Emoto M., Iwasaki H., Kawarabayashi T., Egami D., Yoshitake H., Kikuchi M., Shirakawa K. Primary osteosarcoma of the uterus: report of a case with immunohistochemical analysis. Gynecol. Oncol. 1994;54(3):385–388. (Sep) - PubMed
    1. Hensley M.L. Update on gemcitabine and docetaxel combination therapy for primary and metastatic sarcomas. Curr. Opin. Oncol. 2010;22(4):356–361. (Jul) - PubMed

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