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Case Reports
. 2015 Jul;21(7):1189-91.
doi: 10.3201/eid2107.140981.

Swine Influenza A(H3N2) Virus Infection in Immunocompromised Man, Italy, 2014

Antonio Piralla, Ana Moreno, Maria Ester Orlandi, Elena Percivalle, Chiara Chiapponi, Fausto Vezzoli, Fausto Baldanti; Influenza Surveillance Study Group
Collaborators
Case Reports

Swine Influenza A(H3N2) Virus Infection in Immunocompromised Man, Italy, 2014

Antonio Piralla et al. Emerg Infect Dis. 2015 Jul.

Abstract

Because swine influenza virus infection is seldom diagnosed in humans, its frequency might be underestimated. We report a immunocompromised hematologic patient with swine influenza A(H3N2) virus in 2014 in Italy. Local pigs were the source of this human infection.

Keywords: Italy; Swine influenza; influenza; subtype H3N2; viruses; zoonoses.

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Figures

Figure 1
Figure 1
Phylogenetic trees of the hemagglutinin (A) and neuraminidase (B) genes of swine influenza viruses (SIVs). The 8 genome segment sequences of the A/Pavia/07/2014 strain (black dot, in bold) were submitted to GenBank under accession nos. KJ623706–KJ623713. Scale bars indicate nucleotide substitutions per site.
Figure 2
Figure 2
Amino acid sequence alignment of the hemagglutinin protein of swine influenza virus (SIV) (H3N2) strain A/Pavia/07/2014 (bold) and other SIVs. Antigenic sites A, B, C, D, and E of H3 HA are highlighted in green, magenta, blue, gray, and yellow, respectively, as proposed by others (11). Amino acid changes with respect to the A/Aichi/2/1968 strain are indicated for each strain.
See this image and copyright information in PMC

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