Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015 Jul;73(7):448-62.
doi: 10.1093/nutrit/nuv005. Epub 2015 Apr 28.

Dietary modification and supplementation for the treatment of age-related macular degeneration

Geoffrey K Broadhead  1 , John R Grigg  2 , Andrew A Chang  2 , Peter McCluskey  2
Affiliations
Review

Dietary modification and supplementation for the treatment of age-related macular degeneration

Geoffrey K Broadhead et al. Nutr Rev. 2015 Jul.

Abstract

Age-related macular degeneration (AMD) causes a significant proportion of visual loss in the developed world. Currently, little is known about its pathogenesis, and treatment options are limited. Dietary intake is one of the few modifiable risk factors for this condition. The best-validated therapies remain oral antioxidant supplements based on those investigated in the Age-Related Eye Disease Study (AREDS) and the recently completed Age-Related Eye Disease Study 2 (AREDS2). In this review, current dietary guidelines related to AMD, along with the underlying evidence to support them, are presented in conjunction with current treatment recommendations. Both AREDS and AREDS2 are discussed, as are avenues for further research, including supplementation with vitamin D and saffron. Despite the considerable disease burden of atrophic AMD, few effective therapies are available to treat it, and further research is required.

Keywords: Age-related macular degeneration; antioxidants; diet; dietary supplements..

PubMed Disclaimer

MeSH terms

Supplementary concepts