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Comment
. 2015 Jun 16;42(6):977-9.
doi: 10.1016/j.immuni.2015.06.008.

Complementing T Cells' Functions: Bringing in Metabolism Matters

Mark R Boothby  1 , Ariel L Raybuck  2 , Sung Hoon Cho  3
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Comment

Complementing T Cells' Functions: Bringing in Metabolism Matters

Mark R Boothby et al. Immunity. .
Free article

Abstract

Components of the complement system act directly on T cells to alter conventional and regulatory T cell subsets. In this issue of Immunity, Kolev, Dimeloe, Le Friec et al. (2015) provide evidence of a mechanism by which the complement stimulates sustained mTORC1 activation and regulates cellular metabolism.

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