A Death Notice for In-Vitro-Generated GM-CSF Dendritic Cells?
- PMID: 26084019
- DOI: 10.1016/j.immuni.2015.05.020
A Death Notice for In-Vitro-Generated GM-CSF Dendritic Cells?
Abstract
Mouse bone marrow cells cultured with GM-CSF are often used to generate dendritic cells (DCs); in this issue of Immunity, Helft et al. (2015) show that this classical method produces heterogeneous populations of myeloid cells that are only distantly related to macrophages and DCs found in vivo.
Copyright © 2015 Elsevier Inc. All rights reserved.
Comment in
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Still Alive and Kicking: In-Vitro-Generated GM-CSF Dendritic Cells!Immunity. 2016 Jan 19;44(1):1-2. doi: 10.1016/j.immuni.2015.12.013. Immunity. 2016. PMID: 26789912 No abstract available.
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A Matter of Perspective: Moving from a Pre-omic to a Systems-Biology Vantage of Monocyte-Derived Cell Function and Nomenclature.Immunity. 2016 Jan 19;44(1):5-6. doi: 10.1016/j.immuni.2015.12.020. Immunity. 2016. PMID: 26789914 No abstract available.
Comment on
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GM-CSF Mouse Bone Marrow Cultures Comprise a Heterogeneous Population of CD11c(+)MHCII(+) Macrophages and Dendritic Cells.Immunity. 2015 Jun 16;42(6):1197-211. doi: 10.1016/j.immuni.2015.05.018. Immunity. 2015. PMID: 26084029
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