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. 2015 Jan 20:20:51.
doi: 10.11604/pamj.2015.20.51.5928. eCollection 2015.

Radiological findings in Behçet disease

Chraa Mohamed  1 , Kissani Najib  1 , Lamia Essaadouni  2
Affiliations

Radiological findings in Behçet disease

Chraa Mohamed et al. Pan Afr Med J. .

Abstract

Between 5 and 30% of patients with Behçet's disease will present neurological signs during the course of their illness. In order to evaluate the radiological signs on neuro-behçet disease, we studied consecutive patients in whom the diagnosis of this disease was retained, and who referred from January 2004 to December 2011 to the neurology and internal medicine departments in Mohammed VI universitary hospital in Marrakesh. Using 1.5T magnetic resonance imaging (MRI) with axial and coronal T2- weighted, axial Fluid Attenuated Inversion Recovery (FLAIR), pre- and post-contrast axial, coronal and sagittal T1-weighted sequences. The final number of patients in whom the diagnosis criteria of behçet disease were fulfilled and in whom an MRI was performed was 68 cases. Among these patients, 52 had parenchymal form of neuro-behçet with abnormalities in the MRI, 12 had vascular form and 4 patients had normal MRI. The brainstem, cerebral white matter, basal ganglia, internal capsule, thalamus and spinal cord were involved in forty four, thirty one, thirty, twenty nine, seventeen and four patients, respectively. The cerebral peduncle was the brainstem structure mainly involved with thirty cases followed by the pons with, twenty cases. Midbrain involvement interested forty patients. Brainstem atrophy was seen in eighteen cases. Finally, control MRI were obtained in four cases only, and showed changes in lesions size and shape.

Keywords: MRI; Meuro-behçet disease; brainstem; central nervous system.

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Figures

Figure 1
Figure 1
T2 weighted MRI sequences showing typical presentation of NBD with an association of brainstem and midbrain hypersignal lesions
Figure 2
Figure 2
Flair weighted MRI sequences of two patients showing atypical presentations of neurobehçet disease
Figure 3
Figure 3
Flair weighted MRI sequences showing brainstem lesions with ventral localization
Figure 4
Figure 4
Pseudotumoral forms of neurobehçet disease
Figure 5
Figure 5
T1 weighted MRI sequences showing brainstem atrophy in a patient with NBD
See this image and copyright information in PMC

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