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. 2015 Sep;59(9):5830-3.
doi: 10.1128/AAC.04865-14. Epub 2015 Jun 22.

Case-control study of the risk factors for acquisition of Pseudomonas and Proteus species during tigecycline therapy

Ga Eun Park  1 , Cheol-In Kang  2 , Yu Mi Wi  3 , Jae-Hoon Ko  1 , Woo Joo Lee  1 , Ji Yong Lee  1 , Sun Young Cho  1 , Young Eun Ha  1 , Doo Ryeon Chung  1 , Kyong Ran Peck  1 , Jae-Hoon Song  1
Affiliations

Case-control study of the risk factors for acquisition of Pseudomonas and Proteus species during tigecycline therapy

Ga Eun Park et al. Antimicrob Agents Chemother. 2015 Sep.

Abstract

Tigecycline is an important agent in clinical practice because of its broad-spectrum activity. However, it has no activity against Pseudomonas or Proteus species. We conducted a case-control study to analyze risk factors for the acquisition of Pseudomonas or Proteus spp. during tigecycline therapy. Placement of suction drainage at infected wound sites, ICU stay, and neurologic disease were identified as independent risk factors for the acquisition of Pseudomonas and Proteus spp.

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