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Editorial
. 2015 Aug 3;14(15):2377-8.
doi: 10.1080/15384101.2015.1063288. Epub 2015 Jun 23.

When mismatch repair met translesion synthesis

Anastasia Tsaalbi-Shtylik  1 , Jacob G Jansen, Niels de Wind
Affiliations
Editorial

When mismatch repair met translesion synthesis

Anastasia Tsaalbi-Shtylik et al. Cell Cycle. .
No abstract available

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Figures

Figure 1.
Figure 1.
Responses to (6–4)PP. Most UVC-induced (6–4)PP (red triangle) will be repaired by NER. Unrepaired (6–4)PP are skipped by processive replication, necessitating to invoke error-prone TLS. Inadvertent TLS errors are excised by post-TLS repair. The resulting ss(6–4)PP patches induce checkpoint signaling and, during the subsequent cell cycle, can collapse (not shown). Error-free filling of the gaps induced by post-TLS repair mitigates the mutagenicity of UVC.
See this image and copyright information in PMC

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