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. 1989 Dec;50(12):2117-9.

Effects of colostral antibody on susceptibility of calves to Cryptosporidium parvum infection

J A Harp  1 , D B Woodmansee, H W Moon
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  • PMID: 2610438
Free article

Effects of colostral antibody on susceptibility of calves to Cryptosporidium parvum infection

J A Harp et al. Am J Vet Res. 1989 Dec.
Free article

Erratum in

  • Am J Vet Res 1990 Jul;51(7):1155

Abstract

Effects of colostral antibody on susceptibility of calves to Cryptosporidium parvum infection were examined. Six calves were fed pooled colostrum that contained C parvum antibody, 6 times daily (at 4-hour intervals) for 7 days and then milk replacer for 7 days. Colostrum was obtained from healthy cows or cows inoculated parenterally with C parvum oocysts before parturition. Antibody content was determined in serum and colostrum whey, using an ELISA for anticryptosporidia immunoglobulin. Six calves were fed colostrum from healthy cows 1 time, and then milk replacer 6 times daily for 14 days. On day 1, all calves were challenge exposed with C parvum, PO, and were monitored daily for diarrhea and oocyst shedding. Bovine colostrum containing specific antibody to C parvum, at ELISA titers up to 10,240, was not effective in protecting calves against challenge exposure to C parvum.

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