Final Report of Radiation Therapy Oncology Group Protocol 9003: Provocative, but Limited Conclusions From Exploratory Analyses
- PMID: 26104925
- PMCID: PMC5955397
- DOI: 10.1016/j.ijrobp.2015.02.051
Final Report of Radiation Therapy Oncology Group Protocol 9003: Provocative, but Limited Conclusions From Exploratory Analyses
Conflict of interest statement
Conflict of interest: none.
Comment on
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  Final results of local-regional control and late toxicity of RTOG 9003: a randomized trial of altered fractionation radiation for locally advanced head and neck cancer.Int J Radiat Oncol Biol Phys. 2014 May 1;89(1):13-20. doi: 10.1016/j.ijrobp.2013.12.027. Epub 2014 Mar 7. Int J Radiat Oncol Biol Phys. 2014. PMID: 24613816 Free PMC article. Clinical Trial.
References
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    - Marcial VA, Pajak TF, Chang C, et al. Hyperfractionated photon radiation therapy in the treatment of advanced squamous cell carcinoma of the oral cavity, pharynx, larynx, and sinuses, using radiation therapy as the only planned modality: (preliminary-report) by the Radiation Therapy Oncology Group (RTOG) Int J Radiat Oncol Biol Phys. 1987;13:41–47. - PubMed
 
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    - Bentzen SM, Thames HD. Dose-response relationships for late radiation effects in the head and neck: Regarding the analysis of the RTOG 8313 trial, Fu et al. IJROBP 32:577–588; 1995. Int J Radiat Oncol Biol Phys. 1996;34:523–524. - PubMed
 
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    - Cox JD, Pajak TF, Marcial VA, et al. Interfraction interval is a major determinant of late effects, with hyperfractionated radiation therapy of carcinomas of upper respiratory and digestive tracts—results from Radiation-Therapy Oncology Group protocol 8313. Int J Radiat Oncol Biol Phys. 1991;20:1191–1195. - PubMed
 
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