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Observational Study
. 2015 Jun 23;5(6):e006256.
doi: 10.1136/bmjopen-2014-006256.

Evaluation of the Methods and Management of Acute Coronary Events (EMMACE)-3: protocol for a longitudinal study

O A Alabas  1 , R M West  2 , R G Gillott  3 , R Khatib  3 , A S Hall  3 , C P Gale  4 ; EMMACE-3 Investigators
Collaborators, Affiliations
Observational Study

Evaluation of the Methods and Management of Acute Coronary Events (EMMACE)-3: protocol for a longitudinal study

O A Alabas et al. BMJ Open. .

Abstract

Introduction: Patients with cardiovascular disease are living longer and are more frequently accessing healthcare resources. The Evaluation of the Methods and Management of Acute Coronary Events (EMMACE)-3 national study is designed to improve understanding of the effect of quality of care on health-related outcomes for patients hospitalised with acute coronary syndrome (ACS).

Methods and analysis: EMMACE-3 is a longitudinal study of 5556 patients hospitalised with an ACS in England. The study collects repeated measures of health-related quality of life, information about medications and patient adherence profiles, a survey of hospital facilities, and morbidity and mortality data from linkages to multiple electronic health records. Together with EMMACE-3X and EMMACE-4, EMMACE-3 will assimilate detailed information for about 13 000 patients across more than 60 hospitals in England.

Ethics and dissemination: EMMACE-3 was given a favourable ethical opinion by Leeds (West) Research Ethics committee (REC reference: 10/H131374). On successful application, study data will be shared with academic collaborators. The findings from EMMACE-3 will be disseminated through peer-reviewed publications, at scientific conferences, the media, and through patient and public involvement.

Study registration number: ClinicalTrials.gov Identifier: NCT01808027. Information about the study is also available at EMMACE.org.

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Figures

Figure 1
Figure 1
Regional map of English National Health Service hospitals and patients participating in Evaluation of the Methods and Management of Acute Coronary Events (EMMACE)-3.
Figure 2
Figure 2
Evaluation of the Methods and Management of Acute Coronary Events (EMMACE)-3 cumulative recruitment of participants.
Figure 3
Figure 3
Flow chart of the EMMACE studies. MINAP, Myocardial Ischaemia National Audit Project; NHS, National Service Framework; HES, Hospital Episode Statistics; EQ-5D, EuroQol 5-dimension; EMMACE, Evaluation of the Methods and Management of Acute Coronary Events.
Figure 4
Figure 4
Flow diagram showing number of EMMACE-3 participants at each phase of the study (ACS, acute coronary syndrome; EMMACE, Evaluation of the Methods and Management of Acute Coronary Events).
See this image and copyright information in PMC

References

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Publication types

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