Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2015 Jul;64(7):2322-3.
doi: 10.2337/db15-0331.

Hypoglycemia-Associated Autonomic Failure in Diabetes: Maladaptive, Adaptive, or Both?

Affiliations
Comment

Hypoglycemia-Associated Autonomic Failure in Diabetes: Maladaptive, Adaptive, or Both?

Philip E Cryer. Diabetes. 2015 Jul.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Maladaptive and adaptive aspects of HAAF in diabetes.

Comment on

References

    1. Joy NG, Tate DB, Younk LM, Davis SN. Effects of acute and antecedent hypoglycemia on endothelial function and markers of atherothrombotic balance in healthy humans. Diabetes 2015;64:2571–2580 - PMC - PubMed
    1. Heller SR, Cryer PE. Reduced neuroendocrine and symptomatic responses to subsequent hypoglycemia after 1 episode of hypoglycemia in nondiabetic humans. Diabetes 1991;40:223–226 - PubMed
    1. Dagogo-Jack SE, Craft S, Cryer PE. Hypoglycemia-associated autonomic failure in insulin-dependent diabetes mellitus. Recent antecedent hypoglycemia reduces autonomic responses to, symptoms of, and defense against subsequent hypoglycemia. J Clin Invest 1993;91:819–828 - PMC - PubMed
    1. Giménez M, Gilabert R, Monteagudo J, et al. . Repeated episodes of hypoglycemia as a potential aggravating factor for preclinical atherosclerosis in subjects with type 1 diabetes. Diabetes Care 2011;34:198–203 - PMC - PubMed
    1. Ceriello A, Novials A, Ortega E, et al. . Evidence that hyperglycemia after recovery from hypoglycemia worsens endothelial function and increases oxidative stress and inflammation in healthy control subjects and subjects with type 1 diabetes. Diabetes 2012;61:2993–2997 - PMC - PubMed

Publication types