Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015 Apr;20(4):403-11.

Medicated chewing gum, a novel drug delivery system

Affiliations
Review

Medicated chewing gum, a novel drug delivery system

Abolfazl Aslani et al. J Res Med Sci. 2015 Apr.

Abstract

New formulations and technologies have been developed through oral drug delivery systems' researches. Such researches display significance of oral route amongst patients. We've reviewed all the features associated with medicated chewing gum as a modern drug delivery by introducing the history, advantages and disadvantages, methods of manufacturing, composition differences, evaluation tests and examples of varieties of medicated chewing gums. Acceptance of medicated chewing gum has been augmented through years. The advantages and therapeutic benefits of chewing gum support its development as we can see new formulations with new drugs contained have been produced from past and are going to find a place in market by formulation of new medicated chewing gums. Potential applications of medicated chewing gums are highly widespread as they will be recognized in future. Nowadays standards for qualifying chewing gums are the same as tablets. Patient-centered studies include medicated chewing gums as a delivery system too which creates compliance for patients.

Keywords: Oral drug delivery; medicated chewing gum; patient compliance.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None declared.

Similar articles

Cited by

References

    1. 7th ed. Strasbourg: Directorate for the Quality of Medicine and Health Care of the Council of Europe; 2009. Directorate for the Quality of Medicine and Health Care of the Council of Europe. European Pharmacopoeia; p. 289. 709.
    1. [Last accessed on 2013 July 2]. Available from: http://www.candyfavorites.com/shop/education.php .
    1. Rathbone MJ, Hadgraft J, Roberts MS. New York: CRC Press; 2002. Modified-Release Drug Delivery Technology.
    1. Jacobsen J, Christrup LL, Jensen NH. Medicated chewing gum. Am J Drug Del. 2004;2:75–88.
    1. [Last accessed on 2013 July 15]. Available from: http://www.madehow.com/Volume-1/Chewing-Gum.html .