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Review
. 2015 Jun 25;11(6):e1004866.
doi: 10.1371/journal.ppat.1004866. eCollection 2015 Jun.

Host Delivery of Favorite Meals for Intracellular Pathogens

Yousef Abu Kwaik  1 , Dirk Bumann  2
Affiliations
Review

Host Delivery of Favorite Meals for Intracellular Pathogens

Yousef Abu Kwaik et al. PLoS Pathog. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Schematic overview of host nutrient supply for intracellular pathogens (blue, cytosolic pathogen; green, vacuolar pathogen; AA, amino acids; Glc, glucose; Glyc, glycerol).
Cellular mechanisms that convert polymeric nutrients into small building blocks and deliver them to vacuolar pathogens are shown on the right (1, degradation of proteins to amino acids by proteasomes; 2, endocytosis and degradation in lysosomes; 3, autophagosome formation and delivery to lysosomes; 4, vesicle trafficking and fusion/luminal exchange with pathogen-containing vacuole). Pathways that are stimulated (+) or repressed during hypoxic conditions within inflammatory foci are labelled in purple.
See this image and copyright information in PMC

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