Cardiovascular Health of Patients With Cancer and Cancer Survivors: A Roadmap to the Next Level

Abstract

Many existing and emerging cancer therapies have a significant effect on the cardiovascular health of patients with cancer and cancer survivors. This paper examines current aspects of interdisciplinary cardio-oncology clinical care delivery and education in the United States and outlines how these data provide a platform for future development of the field. We present the results of the nationwide survey on cardio-oncology services, practices, and opinions, conducted among chiefs of cardiology and program directors, which demonstrate ranges of clinical activities and identify significant interest for increased educational opportunities and expert training of cardiovascular physicians in this field. The survey respondents recognized clinical relevance but emphasized lack of national guidelines, lack of funds, and limited awareness and infrastructure as the main challenges for development and growth of cardio-oncology. We discuss potential solutions to unmet needs through interdisciplinary collaboration and the active roles of professional societies and other stakeholders.

Keywords: cancer survivorship; cardio-oncology; cardiovascular risk prevention; cardiovascular toxicity.

Figure 1. Continuum of Cardiovascular Care in Cardio-Oncology

An example of the continuum of cardiovascular care on a timeline of cancer diagnosis, treatment, and survivorship. Patient A represents a patient with no existing cardiovascular disease and patient B represents a patient with a pre-existing cardiovascular condition.

Figure 2. PubMed Citations in “Cardio-Oncology”

Number of PubMed citations using search term “cardio oncology” by year.

Central Illustration. Overview of the Spectrum Of Cardio-Oncology: Bench to Bedside to Community

Partnerships across and within the disciplines of cardiology and oncology in the areas of research (basic, translational, clinical, and population science), education and clinical training, and guidelines and clinical documents development as a potential solution to unmet needs and advancement in patient care.