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Case Reports
. 2016 Apr;159(4):1231-3.
doi: 10.1016/j.surg.2015.03.012. Epub 2015 May 1.

In vivo detection of catecholamines by magnetic resonance spectroscopy: A potential specific biomarker for the diagnosis of pheochromocytoma

Alessio Imperiale  1 , Stephanie Battini  2 , Gerlinde Averous  3 , Didier Mutter  4 , Bernard Goichot  5 , Philippe Bachellier  6 , Karel Pacak  7 , David Taïeb  8 , Izzie-Jacques Namer  9
Affiliations
Case Reports

In vivo detection of catecholamines by magnetic resonance spectroscopy: A potential specific biomarker for the diagnosis of pheochromocytoma

Alessio Imperiale et al. Surgery. 2016 Apr.
No abstract available

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Figures

Fig 1.
Fig 1.
Results of upper abdomen MRI (A), in vivo respiratory-triggered proton single-voxel 1H-MRS (B), and ex vivo 1H-HRMAS NMR (D), respectively, performed in a pheochromocytoma (C). The signal detected at about 7 ppm (*) corresponds to the spectral signature of the catecholamine-specific 3,4-dihydroxybenzene group detected in pheochromocytoma by respiratory triggered single voxel 1H-MRS then confirmed by 1H-HRMAS NMR.
Fig 2.
Fig 2.
Results of upper abdomen MRI (A), in vivo respiratory-triggered single-voxel 1H-MRS (B), and ex vivo 1H-HRMAS NMR (D), respectively, performed in adrenocortical adenoma (C). No catecholamine-specific signal was detectable neither by 1H-MRS nor by 1H-HRMAS NMR (**) at about 7 ppm.
See this image and copyright information in PMC

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