Consensus best practice pathway of the UK Scleroderma Study Group: digital vasculopathy in systemic sclerosis

Abstract

Objective: Digital vasculopathy (comprising RP, digital ulceration and critical digital ischaemia) is responsible for much of the pain and disability experienced by patients with SSc. However, there is a limited evidence base to guide clinicians in the management of SSc-related digital vasculopathy. Our aim was to produce recommendations that would be helpful for clinicians, especially for those managing patients outside specialist centres.

Methods: The UK Scleroderma Study Group set up several working groups to develop a number of consensus best practice pathways for the management of SSc-specific complications, including digital vasculopathy.

Results: This overview presents the background and best practice consensus pathways for SSc-related RP, digital ulceration and critical ischaemia. Examples of drug therapies, including doses, are suggested in order to inform prescribing practice.

Conclusion: A number of treatment algorithms are provided that are intended to provide the clinician with accessible reference tools for use in daily management.

Keywords: Raynaud’s phenomenon; critical digital ischaemia; digital ulcer; digital vasculopathy; scleroderma; systemic sclerosis.