Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Jan;88(1):180-3.
doi: 10.1002/jmv.24315. Epub 2015 Jul 20.

Reliability of the INSTI® rapid test for the diagnosis of HIV-1 non-B subtypes and recombinant variants

Jeanne Goupil de Bouillé  1 , Gwénaël Le Moal  2 , Laurent Hocqueloux  1 , Aurélie Guigon  3 , David Plainchamp  2 , Geneviève Giraudeau  4 , Aurélie Theillay  1 , Anne Languille  1 , Laurent Bélec  5 , Thierry Prazuck  1
Affiliations

Reliability of the INSTI® rapid test for the diagnosis of HIV-1 non-B subtypes and recombinant variants

Jeanne Goupil de Bouillé et al. J Med Virol. 2016 Jan.

Abstract

Data regarding the efficacy of Rapid HIV tests (RHTs) in detecting non-B subtype HIV-1 are limited. We evaluated the sensitivity of the INSTI® test for the detection of HIV-1 antibodies for the diagnosis of HIV-1 non-B subtypes and recombinant variants. We identified adults with HIV-1 infection due to non-B subtypes and recombinant variants. The participants were re-tested with INSTI® test. We included 258 patients. Overall, the INSTI® test sensitivity was 98.4% (95%CI: 96.9-99.9%). For the major CRF_02AG subtype, the sensitivity was 99.0% (95%CI: 97.1-100%). The HIV INSTI® test is reliable for the detection of various non-B HIV-1 antibodies.

Keywords: HIV Subtype; circulating recombinant form; diagnosis capillary blood test; non-B subtype; rapid HIV test.

PubMed Disclaimer

Publication types

LinkOut - more resources