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. 2013 Dec;6(6):653-4.
doi: 10.1093/ckj/sft110. Epub 2013 Sep 20.

Calciphylaxis

Affiliations

Calciphylaxis

G H Neild et al. Clin Kidney J. 2013 Dec.
No abstract available

Keywords: calcific uremic arteriolopathy; calciphylaxis.

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Figures

Fig. 1.
Fig. 1.
Dry gangrene of the fingers (A and B) and dusky red discoloration of the right great toe (C) are shown. Progression of the gangrene of the fingers (D and E) and development of gangrenous necrosis of the toes (F) are shown. Plain radiographs demonstrating marked vascular calcification of the hands and feet (G–J). Skin biopsy revealing calcification (K) and microthrombosis (L and M) of small subcutaneous blood vessels consistent with calciphylaxis. Tissue sections were stained according to von Kossa method (K) and with Hemotoxylin and eosin stain (L and M).

References

    1. Wilmer WA, Magro CM. Calciphylaxis: emerging concepts in prevention, diagnosis, and treatment. Semin Dial. 2002;15:172–186. - PubMed
    1. Weenig RH. Pathogenesis of calciphylaxis: Hans Selye to nuclear factor kappa-B. J Am Acad Dermatol. 2008;58:458–471. - PubMed
    1. Vedvyas C, Winterfield LS, Vleugels RA. Calciphylaxis: a systematic review of existing and emerging therapies. J Am Acad Dermatol. 2012;67:e253–e260. - PubMed

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