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Review
. 2015 Nov;24(11):821-6.
doi: 10.1111/exd.12785. Epub 2015 Aug 25.

MicroRNAs (miRNAs) in the control of HF development and cycling: the next frontiers in hair research

Thomas Andl  1 , Natalia V Botchkareva  2
Affiliations
Review

MicroRNAs (miRNAs) in the control of HF development and cycling: the next frontiers in hair research

Thomas Andl et al. Exp Dermatol. 2015 Nov.

Abstract

Hair follicle development and its postnatal regeneration are characterized by dramatic changes in its microanatomy and cellular activity, which are controlled by multiple signalling pathways, transcription factors and epigenetic regulators, including microRNAs (miRNAs). miRNAs and their targets form remarkably diverse regulatory networks, playing a key role in the execution of gene expression programmes in the different cell lineages of the hair follicle. This review summarizes the roles of miRNAs in the control of hair follicle development, cycling and hair pigmentation, emphasizes the remaining problems/unanswered questions, and provides future directions in this rapidly growing and exciting area of research.

Keywords: development; hair cycle; hair follicle; microRNA.

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Conflict of interest statement

Conflict of interests

The authors declare no conflicting interests.

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