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. 1989;52(1-2):79-82.
doi: 10.1159/000132845.

Sister chromatid exchanges in the human active and inactive X chromosomes

A Zhang  1 , M S Lin, M G Wilson, A Fujimoto
Affiliations

Sister chromatid exchanges in the human active and inactive X chromosomes

A Zhang et al. Cytogenet Cell Genet. 1989.

Abstract

Four human female fibroblast strains with an i(Xq) or derivative X chromosome as a cytological marker for the inactive X chromosome were used to determine the frequency of sister chromatid exchanges (SCEs) in the active and inactive X chromosomes. No significant difference in SCE frequency between the active and inactive X chromosomes was observed. Therefore, the state of chromatin condensation and the late DNA replication in the facultative heterochromatin of the inactive X chromosome do not appear to influence the SCE frequency.

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