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Review
. 2015:2015:143720.
doi: 10.1155/2015/143720. Epub 2015 Jun 1.

Metal-Based Nanoparticles and the Immune System: Activation, Inflammation, and Potential Applications

Yueh-Hsia Luo  1 , Louis W Chang  2 , Pinpin Lin  3
Affiliations
Review

Metal-Based Nanoparticles and the Immune System: Activation, Inflammation, and Potential Applications

Yueh-Hsia Luo et al. Biomed Res Int. 2015.

Abstract

Nanomaterials, including metal-based nanoparticles, are used for various biological and medical applications. However, metals affect immune functions in many animal species including humans. Different physical and chemical properties induce different cellular responses, such as cellular uptake and intracellular biodistribution, leading to the different immune responses. The goals of this review are to summarize and discuss the innate and adaptive immune responses triggered by metal-based nanoparticles in a variety of immune system models.

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Figure 1
Figure 1
Metal-based nanoparticles interaction with immune system.
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