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. 2015 Apr 15;8(4):4922-31.
eCollection 2015.

An updated meta-analysis of laparoscopic versus open pyeloplasty for ureteropelvic junction obstruction in children

Yidong Huang  1 , Yang Wu  1 , Wei Shan  1 , Li Zeng  1 , Lugang Huang  1
Affiliations

An updated meta-analysis of laparoscopic versus open pyeloplasty for ureteropelvic junction obstruction in children

Yidong Huang et al. Int J Clin Exp Med. .

Abstract

Purpose: To further explore the feasibility and safety of laparoscopic pyeloplasty (LP) in children with ureteropelvic junction obstruction compared with open pyeloplasty (OP).

Methods: PUBMED, Web of science and Cochrane library were searched until Oct. 2014 to find eligible studies. WMD, OR, RD and their 95% CIs were used to estimate the difference. Baseline such as age, gender and crossing vessel, perioperative outcomes such as length of stay, operative time, overall complications, and success rate were compared. All the meta-analyses were performed in Revman 5.2.

Results: 15 comparative studies and one RCT were eligible and included in the meta-analysis. Compared with OP, LP groups might be associated with shorted length of hospital stay (WMD: -1.92, 95% CI: -2.45--1.39), reduced complications (OR: 0.71, 95% CI: 0.49-1.01) and equal success rate (RD: 0.01, 95% CI: -0.02-0.04), but prolonged operative time (WMD: 48.64, 95% CI: 31.16-66.12).

Conclusion: Our findings supported that laparoscopic pyeloplasty is feasibility and safety in the treatment of UPJ obstruction in children, especially in high-volume centers with experienced experts. Considering the select bias and recall bias, more RCTs are required to further explore the efficiencies of LP.

Keywords: Laparoscopic pyeloplasty; children; meta-analysis; ureteropelvic junction obstruction.

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Figures

Figure 1
Figure 1
Flowchart of this meta-analysis.
Figure 2
Figure 2
Forest plot and meta-analysis of side of UPJ obstruction in children.
Figure 3
Figure 3
Forest plot and meta-analysis of crossing vessel in children with UPJ obstruction.
Figure 4
Figure 4
Forest plot and meta-analysis of operative time comparing LP and OP in children with UPJ obstruction.
Figure 5
Figure 5
Forest plot and meta-analysis of length of hospital stay comparing LP and OP in children with UPJ obstruction.
Figure 6
Figure 6
Forest plot and meta-analysis of overall complication comparing LP and OP in children with UPJ obstruction.
Figure 7
Figure 7
Forest plot and meta-analysis of success rate comparing LP and OP in children with UPJ obstruction.
Figure 8
Figure 8
Funnel plot of overall complication comparing LP and OP in children with UPJ obstruction.
See this image and copyright information in PMC

References

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