Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2015 Jun 27;7(6):98-101.
doi: 10.4240/wjgs.v7.i6.98.

Gastrointestinal stromal tumour presenting as palpable abdominal mass: A rare entity

Manoj R Bhambare  1 , Jayashri S Pandya  1 , Sudatta B Waghmare  1 , Tilakdas S Shetty  1
Affiliations
Case Reports

Gastrointestinal stromal tumour presenting as palpable abdominal mass: A rare entity

Manoj R Bhambare et al. World J Gastrointest Surg. .

Abstract

Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal tumour of gastro-intestinal tract. Annual incidence of GIST in United States is approximately 3000-4000. Clinical presentation of GIST varies with location and size of tumour but GIST presenting with palpable abdominal mass is rare. We report a case of 38 years old male who presented with large abdominal lump. Computed tomography (CT) scan showed a large solid-cystic lesion encasing second part of duodenum and distal common bile duct. On CT differential diagnosis of Leiomyoma, Leiomyosarcoma and GIST were made. The diagnosis of GIST was confirmed by immune-histochemical study of the biopsy material. Patient underwent pancreaticodudenectomy. Post-operative course was uneventful. Patient was started on Imatinib therapy post-operatively. No recurrence noted at six months follow up.

Keywords: Abdominal mass; Gastrointestinal stromal tumours; Imatinib; Pancreaticoduodenectomy.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Computed tomography abdomen showing tumour encasing second part of duodenum and dilated common bile duct.
Figure 2
Figure 2
Microscopic findings (hematoxilin-eosin).
Figure 3
Figure 3
Gross specimen showing tumour.
See this image and copyright information in PMC

References

    1. Dematteo RP, Ballman KV, Antonescu CR, Maki RG, Pisters PW, Demetri GD, Blackstein ME, Blanke CD, von Mehren M, Brennan MF, et al. Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial. Lancet. 2009;373:1097–1104. - PMC - PubMed
    1. Tan CB, Zhi W, Shahzad G, Mustacchia P. Gastrointestinal stromal tumors: a review of case reports, diagnosis, treatment, and future directions. ISRN Gastroenterol. 2012;2012:595968. - PMC - PubMed
    1. Laperouse P, Raines D, Diamond K, Rivera S, Newman W, Hew AY, Lopez FA. Gastrointestinal stromal tumors: a case report and review of the literature. J La State Med Soc. 2008;160:128–33; quiz 134. - PubMed
    1. Patil S, Jain S, Kaza RC, Chamberlain RS. Giant gastrointestinal stromal tumor presenting as a palpable abdominal mass: an unusual presentation. ISRN Surg. 2011;2011:894829. - PMC - PubMed
    1. Dorfman DM, Bui MM, Tubbs RR, Hsi ED, Fitzgibbons PL, Linden MD, Rickert RR, Roche PC. The CD117 immunohistochemistry tissue microarray survey for quality assurance and interlaboratory comparison: a College of American Pathologists Cell Markers Committee Study. Arch Pathol Lab Med. 2006;130:779–782. - PubMed

Publication types

LinkOut - more resources