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Observational Study
. 2015 Jun;104(6):433-42.
doi: 10.5935/abc.20150031. Epub 2015 Apr 3.

I Brazilian Registry of Heart Failure - Clinical Aspects, Care Quality and Hospitalization Outcomes

[Article in English, Portuguese]
Denilson Campos de Albuquerque  1 , João David de Souza Neto  2 , Fernando Bacal  3 , Luiz Eduardo Paim Rohde  4 , Sabrina Bernardez-Pereira  5 , Otavio Berwanger  5 , Dirceu Rodrigues Almeida  6 ; Investigadores Estudo BREATHE
Collaborators, Affiliations
Observational Study

I Brazilian Registry of Heart Failure - Clinical Aspects, Care Quality and Hospitalization Outcomes

[Article in English, Portuguese]
Denilson Campos de Albuquerque et al. Arq Bras Cardiol. 2015 Jun.

Erratum in

  • Correction.
    Arq. Bras. Cardiol. Arq. Bras. Cardiol. Arq Bras Cardiol. 2015 Aug;105(2):208. doi: 10.5935/abc.20150103. Arq Bras Cardiol. 2015. PMID: 26352184 Free PMC article. No abstract available.

Abstract

Background: Heart failure (HF) is one of the leading causes of hospitalization in adults in Brazil. However, most of the available data is limited to unicenter registries. The BREATHE registry is the first to include a large sample of hospitalized patients with decompensated HF from different regions in Brazil.

Objective: Describe the clinical characteristics, treatment and prognosis of hospitalized patients admitted with acute HF.

Methods: Observational registry study with longitudinal follow-up. The eligibility criteria included patients older than 18 years with a definitive diagnosis of HF, admitted to public or private hospitals. Assessed outcomes included the causes of decompensation, use of medications, care quality indicators, hemodynamic profile and intrahospital events.

Results: A total of 1,263 patients (64±16 years, 60% women) were included from 51 centers from different regions in Brazil. The most common comorbidities were hypertension (70.8%), dyslipidemia (36.7%) and diabetes (34%). Around 40% of the patients had normal left ventricular systolic function and most were admitted with a wet-warm clinical-hemodynamic profile. Vasodilators and intravenous inotropes were used in less than 15% of the studied cohort. Care quality indicators based on hospital discharge recommendations were reached in less than 65% of the patients. Intrahospital mortality affected 12.6% of all patients included.

Conclusion: The BREATHE study demonstrated the high intrahospital mortality of patients admitted with acute HF in Brazil, in addition to the low rate of prescription of drugs based on evidence.

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Conflict of interest statement

Potential Conflict of Interest

No potential conflict of interest relevant to this article was reported.

Figures

Figure 1
Figure 1
Distribution of etiologies of heart failure in the BREATHE registry. * DCM: dilated cardiomyopathy; † QT: secondary to chemotherapy.
Figure 2
Figure 2
Hemodynamic profile on hospital admission.
Figure 3
Figure 3
Medications administered during the hospital stay. * ACEi: angiotensin converting enzyme inhibitor; †ARB: angiotensin II receptor blocker.
Figure 4
Figure 4
Guidelines on hospital discharge according to the indicators of care quality during hospitalization for heart failure (according to the JCAHO*). * Joint Commission on Accreditation of Healthcare Organization. † Applicable to smokers
Supplement II
Supplement II
Flow diagram of the BREATHE study.
See this image and copyright information in PMC

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