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Randomized Controlled Trial
. 2015;21(6):544-50.
doi: 10.5761/atcs.oa.15-00118. Epub 2015 Jun 30.

The Effects of Near-Infrared Spectroscopy on the Neurocognitive Functions in the Patients Undergoing Coronary Artery Bypass Grafting with Asymptomatic Carotid Artery Disease: A Randomized Prospective Study

Ibrahim Kara  1 , Alper Erkin, Hakan Saclı, Mucahit Demirtas, Bilal Percin, Mevriye Serpil Diler, Kaan Kırali
Affiliations
Randomized Controlled Trial

The Effects of Near-Infrared Spectroscopy on the Neurocognitive Functions in the Patients Undergoing Coronary Artery Bypass Grafting with Asymptomatic Carotid Artery Disease: A Randomized Prospective Study

Ibrahim Kara et al. Ann Thorac Cardiovasc Surg. 2015.

Abstract

Purpose: The purpose of this study was to research the use of near-infrared spectroscopy (NIRS) on the neurocognitive functions in the patients undergoing coronary artery bypass grafting (CABG) with asymptomatic carotid artery disease.

Methods: The study design was carried out with the participation of 79 patients in a prospective, randomized and double blind control method. The patients were separated into two groups as NIRS (n = 43) and no NIRS (n = 36). A neurocognitive test was applied preoperatively and postoperatively to all patients before discharge. Cognitive functions were evaluated by applying the Montreal Cognitive Assessment test (MoCA).

Results: The decrease in the postoperative score of mean MoCA in no NIRS group was statistically significant when compared to preoperatively (p <0.001). Postoperative mean MoCA score was found to be significantly higher in NIRS group (NIRS: 26.8 ± 1.9 vs. no NIRS: 23.6 ± 2.5, p <0.001). It has been determined that there was a moderately positive significant correlation between the increase in the NIRS used patients (%) and increase in the MoCA score of the patients (r = 0.59, p <0.001).

Conclusion: Intraoperative NIRS usage in the patients undergoing CABG with carotid artery disease might be useful due to its postoperative positive effects on the cognitive functions.

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Figures

Fig. 1
Fig. 1
The algorithm for the treatment of cerebral desaturation. FiO2: fraction of inspired oxygen; Hct: hematocrit; MAP: mean arterial pressure; PaCO2: partial carbon dioxide; rSO2: regional cerebral oxygenation
Fig. 2
Fig. 2
The correlation between the number of the patients (%) in NIRS and no NIRS groups and MoCA scores. MoCA: Montreal Cognitive Assessment; NIRS: near-infrared spectroscopy
See this image and copyright information in PMC

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