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Comment
. 2015 Jul 2;162(1):16-7.
doi: 10.1016/j.cell.2015.06.033.

From Prescription to Transcription: Genome Sequence as Drug Target

Cong Guo  1 , Anthony M D'Ippolito  1 , Timothy E Reddy  2
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From Prescription to Transcription: Genome Sequence as Drug Target

Cong Guo et al. Cell. .
Free article

Abstract

Personalizing treatments to account for genetically mediated differences in drug responses is an exciting opportunity to improve patient outcomes. In this issue, Soccio et al. reveal new mechanisms by which non-coding variants alter the activity of the anti-diabetic drug rosiglitazone.

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