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. 2015 Jul 2;17(1):1-3.
doi: 10.1016/j.stem.2015.06.011.

Direct Reprogramming of RESTing Astrocytes

Chengzhong Wang  1 , Helen Fong  1 , Yadong Huang  2
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Direct Reprogramming of RESTing Astrocytes

Chengzhong Wang et al. Cell Stem Cell. .
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Abstract

Understanding the mechanisms underlying neuronal fate determination will provide important insights into brain development and regenerative approaches to neurological diseases. Now in Cell Stem Cell, Masserdotti et al. (2015) use neuronal conversion of astrocytes to dissect transcriptional mechanisms of fate determination and identify circuits that mediate cellular identity.

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