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. 2015 Aug 11;51(62):12395-8.
doi: 10.1039/c5cc04508h.

Fluorophore ATCUN complexes: combining agent and probe for oxidative DNA cleavage

C Wende  1 , N Kulak
Affiliations

Fluorophore ATCUN complexes: combining agent and probe for oxidative DNA cleavage

C Wende et al. Chem Commun (Camb). .

Abstract

DNA can be oxidatively cleaved by copper complexes of the ATCUN peptide (amino terminal Cu(II)- and Ni(II)-binding motif). In order to investigate the fate of the metal ion throughout this process, we have exploited quenching/dequenching effects of conjugated fluorophores.

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