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Review
. 2015 Aug;13(8):497-508.
doi: 10.1038/nrmicro3491. Epub 2015 Jul 6.

A functional perspective on phenotypic heterogeneity in microorganisms

Martin Ackermann  1
Affiliations
Review

A functional perspective on phenotypic heterogeneity in microorganisms

Martin Ackermann. Nat Rev Microbiol. 2015 Aug.

Abstract

Most microbial communities consist of a genetically diverse assembly of different organisms, and the level of genetic diversity plays an important part in community properties and functions. However, biological diversity also arises at a lower level of biological organization, between genetically identical cells that reside in the same microenvironment. In this Review, I outline the molecular mechanisms responsible for phenotypic heterogeneity and discuss how phenotypic heterogeneity allows genotypes to persist in fluctuating environments. I also describe how it promotes interactions between phenotypic subpopulations in clonal groups, providing microbial groups with new functionality.

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