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Clinical Trial
. 2015 Jul 6;10(7):e0132076.
doi: 10.1371/journal.pone.0132076. eCollection 2015.

Incidence and Geographic Distribution of Extensively Drug-Resistant Tuberculosis in KwaZulu-Natal Province, South Africa

Jennifer R Lim  1 , Neel R Gandhi  2 , Thuli Mthiyane  3 , Koleka Mlisana  4 , Julie Moodley  5 , Prenika Jaglal  5 , Neeshan Ramdin  6 , James C M Brust  1 , Nazir Ismail  7 , Roxana Rustomjee  8 , N Sarita Shah  1
Affiliations
Clinical Trial

Incidence and Geographic Distribution of Extensively Drug-Resistant Tuberculosis in KwaZulu-Natal Province, South Africa

Jennifer R Lim et al. PLoS One. .

Abstract

South Africa is experiencing a widespread drug-resistant tuberculosis epidemic, although data are limited regarding the current situation. This study finds that the extensively drug-resistant tuberculosis (XDR-TB) incidence in KwaZulu-Natal increased to 3.5 cases/100,000 (776 cases) in 2011-2012. XDR-TB cases are widely distributed geographically, with the majority of districts experiencing a rise in incidence.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Change in incidence of XDR-TB in KwaZulu-Natal province, South Africa, 2007 to 2010–12.
Panel A shows the XDR-TB incidence (per 100,000 population) in each district in 2007. Panel B shows the average XDR-TB incidence by district in 2010–2012. The size of the circles is proportional to the incidence rate. The colors in panel B represents the change in incidence compared to 2007 data: red, increase; green, decrease.
See this image and copyright information in PMC

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