[Changes in the cardiac vascular bed in dilated and hypertrophic cardiomyopathy]

Abstract

A complex pathomorphological examination of 46 hearts from subjects who had died of dilated (34 cases) and hypertrophic (12 cases) cardiomyopathies was performed to reveal the changes occurred in the vascular bed. For this, post-mortem coronary angiography, routine anatomic method developed by the WHO, morphometric, histological, and statistical methods were applied. In dilated cardiomyopathy, there were dilatory manifestations in the coronary arteries and vessels of microcirculation along with increased volumetric density of ventricular vascularization. Hypertrophic cardiomyopathy was characterized by a specific rearrangement in the presence of the "intensive coronarogram symptom", microvascular plexus, myocardial muscular bridges, and heterogeneous manifestations of microvessels with decreased capillarization.