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Review
. 2015 Sep;12(3):362-72.
doi: 10.1007/s11904-015-0276-6.

The role of viral co-infection in HIV-associated non-AIDS-related cancers

David J Riedel  1 , Lydia S Tang, Anne F Rositch
Affiliations
Review

The role of viral co-infection in HIV-associated non-AIDS-related cancers

David J Riedel et al. Curr HIV/AIDS Rep. 2015 Sep.

Abstract

HIV-infected individuals are at increased risk for most types of cancer, including those typically classified as non-AIDS-defining cancers (NADCs). This increased risk is likely multifactorial, but a prominent risk factor for the increased rate of some cancers is co-infection with oncogenic viruses. Anal cancer, hepatocellular carcinoma, and Hodgkin lymphoma are three of the most common NADCs, and they are associated with co-infection with human papillomavirus, hepatitis B and C, and Epstein Barr virus, respectively. This review will examine the epidemiology, pathogenesis, and future trends around these virally associated NADCs frequently found in HIV-infected individuals.

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Conflict of interest statement

Conflict of Interest: David J. Riedel, Lydia S. Tang, and Anne F. Rositch all declare no conflicts of interest.

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