Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Oct;39(10):2011-6.
doi: 10.1007/s00264-015-2853-0. Epub 2015 Jul 9.

Myocardial ischaemia after hip and knee arthroplasty: incidence and risk factors

Anne Ruth Bass  1 , Tomás Rodriguez  2 , Gina Hyun  2 , Francisco Gerardo Santiago  3 , Jacqueline Ilji Kim  4 , Scott Christopher Woller  5 , Brian Foster Gage  2
Affiliations

Myocardial ischaemia after hip and knee arthroplasty: incidence and risk factors

Anne Ruth Bass et al. Int Orthop. 2015 Oct.

Abstract

Purpose: Because the occurrence of postoperative myocardial ischaemia (MI) predicts subsequent cardiac morbidity and mortality, we determined the prevalence of and risk factors for MI in hip and knee arthroplasty patients.

Methods: High-sensitivity cardiac troponin T (hs-cTnT) was measured on stored samples from postoperative day two in 394 hip and knee arthroplasty patients ≥ 65 years of age enrolled in the Genetics-InFormatics Trial (GIFT).

Results: Fifty-three (13.5 %) participants had MI, of whom only three were diagnosed clinically during their hospitalisation. The risk of MI increased with age [odds ratio (OR) 3.52 per decade, 95 % confidence interval (CI) 2.00-6.19] and diabetes (OR 2.23, 95 % CI 1.04-4.77). MI was rarer with statins (OR 0.74, 95 % CI 0.40-1.35) and more common with hypertension, coronary artery disease and tobacco use, although these were not statistically significant.

Conclusions: Subclinical MI occurs frequently after arthroplasty. Diabetic and elderly patients are at highest risk.

Keywords: Arthroplasty; Myocardial ischaemia; Postoperative complication; Risk factor; Statin; Troponin.

PubMed Disclaimer

Figures

Figure 1
Figure 1
See this image and copyright information in PMC

References

    1. CDC . FastStats: Inpatient surgery. 2013.
    1. Memtsoudis SG, Gonzalez Della Valle A, Besculides MC, Gaber L, Sculco TP. In-hospital complications and mortality of unilateral, bilateral, and revision TKA: Based on an estimate of 4,159,661 discharges. Clin Orthop Relat Res. 2008;466:2617–2627. doi: 10.1007/s11999-008-0402-5. - PMC - PubMed
    1. Hietala P, Strandberg M, Strandberg N, Gullichsen E, Airaksinen KE. Perioperative myocardial infarctions are common and often unrecognized in patients undergoing hip fracture surgery. J Trauma Acute Care Surg. 2013;74:1087–1091. doi: 10.1097/TA.0b013e3182827322; 10.1097/TA.0b013e3182827322. - PubMed
    1. Chong CP, van Gaal WJ, Savige J, Lim WK. Cardiac injury and troponin testing after orthopaedic surgery. Injury. 2011;42:855–863. - PubMed
    1. Dawson-Bowling S, Chettiar K, Cottam H, Worth R, Forder J, Fitzgerald-O’Connor I, Walker D, Apthorp H. Troponin T as a predictive marker of morbidity in patients with fractured neck of femur. Injury. 2008;39:775–780. doi: 10.1016/j.injury.2008.01.025; 10.1016/j.injury.2008.01.025. - PubMed

Publication types