Aspirin-Induced Acute Liver Injury
- PMID: 26157904
- PMCID: PMC4435341
- DOI: 10.14309/crj.2014.81
Aspirin-Induced Acute Liver Injury
Abstract
Aspirin is thought to be a relatively safe drug in adults. The association of aspirin and Reye syndrome in children is well documented. We report a 41-year-old female with pericarditis who was treated with high-dose aspirin and developed subsequent acute liver injury. After discontinuation of aspirin, liver enzyme elevation and right upper quadrant pain both resolved. We conclude that high-dose aspirin should be considered as a potentially hepatotoxic agent.
References
-
- Lee WM. Drug-induced hepatotoxicity. N Engl J Med. 2003;349(5):474–485. - PubMed
-
- Sgro C, Clinard F, Ouazir K, et al. . Incidence of drug-induced hepatic injuries: A French population-based study. Hepatology. 2002;36(2):451–455. - PubMed
-
- Lee W. Etiologies of acute liver failure. Semin Liver Dis. 2008;28(2):142–152. - PubMed
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