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. 2015 Jun;32(3):229-34.
doi: 10.5114/pdia.2014.44028. Epub 2015 Jun 15.

Mantle cell lymphoma with skin involvement

Agnieszka Kalińska-Bienias  1 , Bogna Ziarkiewicz-Wróblewska  2 , Cezary Kowalewski  1 , Katarzyna Woźniak  1
Affiliations

Mantle cell lymphoma with skin involvement

Agnieszka Kalińska-Bienias et al. Postepy Dermatol Alergol. 2015 Jun.
No abstract available

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Figures

Figure 1
Figure 1
Confluent skin infiltration on the face (A) and the ear (B)
Figure 2
Figure 2
Histological and immunohistochemical findings of the patient's skin (A–C), lymph node (D–F) and bone marrow (G–H): A – proliferation of small to medium-sized atypical lymphoid cells (hematoxylin-eosin stain, 100×), B – expression of CD20 by neoplastic cells (100×), C – no expression of CD3 (100×), D – diffuse proliferation of lymphoid cells (hematoxylin- eosin stain, 200×), E – expression of CD5 by neoplastic cells (200×), F – staining with antibody to Ki 67 (200×), G – diffuse proliferation of lymphoid cells (hematoxylin-eosin stain, 200×), H – neoplastic cells expressed cyclin D1 (200×)
See this image and copyright information in PMC

References

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    1. Moody BR, Bartlett NL, George DW, et al. Cyclin D1 as an aid in the diagnosis of mantle cell lymphoma in skin biopsies: a case report. Am J Dermatopathol. 2001;23:470–6. - PubMed
    1. Phelps A, Gorgan M, Elaba Z, et al. CD10-positive blastoid mantle cell lymphoma with secondary cutaneous involvement. J Cutan Pathol. 2013;40:765–7. - PubMed
    1. Lynch DW, Verma R, Larson E, et al. Primary cutaneous mantle cell lymphoma with blastic features: report of a rare case with special reference to staging and effectiveness of chemotherapy. J Cutan Pathol. 2012;39:449–53. - PubMed

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