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. 2015 Aug 7;17(15):3670-3.
doi: 10.1021/acs.orglett.5b01584. Epub 2015 Jul 10.

Homogeneous Gold-Catalyzed Glycosylations in Continuous Flow

Stefan Matthies  1   2 , D Tyler McQuade  1   3 , Peter H Seeberger  1   2
Affiliations

Homogeneous Gold-Catalyzed Glycosylations in Continuous Flow

Stefan Matthies et al. Org Lett. .

Abstract

The use of versatile alkynyl-building blocks that are activated by gold(I)-catalysis is demonstrated to efficiently generate a variety of glycosides in continuous flow. The application of a continuous flow setting to gold(I)-catalyzed glycosylations enables very short reaction times and excellent control of the reaction conditions.

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