Second line therapy in malignant pleural mesothelioma: A systematic review
- PMID: 26162564
- DOI: 10.1016/j.lungcan.2015.06.018
Second line therapy in malignant pleural mesothelioma: A systematic review
Abstract
After the implementation of standard first line chemotherapy with platinum and antifolates in pleural mesothelioma, patients are confronted with a need for second line treatment at relapse or progression. We conducted a systematic review of the literature for the activity, effectiveness and toxicity of second line treatment. The results are presented according to the class of drugs: chemotherapy and targeted or biological agent.
Keywords: Biological; Chemotherapy; Mesothelioma; Meta-analysis; Outcome; Second line; Targeted treatment; Treatment.
Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
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