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Meta-Analysis
. 2015 Sep;89(3):223-31.
doi: 10.1016/j.lungcan.2015.06.018. Epub 2015 Jun 23.

Second line therapy in malignant pleural mesothelioma: A systematic review

Affiliations
Meta-Analysis

Second line therapy in malignant pleural mesothelioma: A systematic review

Wieneke A Buikhuisen et al. Lung Cancer. 2015 Sep.

Abstract

After the implementation of standard first line chemotherapy with platinum and antifolates in pleural mesothelioma, patients are confronted with a need for second line treatment at relapse or progression. We conducted a systematic review of the literature for the activity, effectiveness and toxicity of second line treatment. The results are presented according to the class of drugs: chemotherapy and targeted or biological agent.

Keywords: Biological; Chemotherapy; Mesothelioma; Meta-analysis; Outcome; Second line; Targeted treatment; Treatment.

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