Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 2015 Dec;16(4):631-8.
doi: 10.1007/s10561-015-9512-y. Epub 2015 Jul 11.

Long-term outcomes of the use of allogeneic, radiation-sterilised bone blocks in reconstruction of the atrophied alveolar ridge in the maxilla and mandible

Marta Krasny  1   2 , Kornel Krasny  3 , Piotr Fiedor  4 , Małgorzata Zadurska  5 , Artur Kamiński  6
Affiliations
Clinical Trial

Long-term outcomes of the use of allogeneic, radiation-sterilised bone blocks in reconstruction of the atrophied alveolar ridge in the maxilla and mandible

Marta Krasny et al. Cell Tissue Bank. 2015 Dec.

Abstract

Increasingly dental surgeons face the challenge of reconstruction of the height and/or thickness of the alveolar ridge as more and more patients wish to have permanent restoration of their dental defects based on intraosseous implants. Evaluation of human allogeneic bone tissue grafts in reconstruction of atrophied alveolar ridge as a pre-implantation procedure. The material comprised 21 patients aged 19-63, treated between 2009 and 2012 by the same surgeon. Restoration of bone tissue defects was performed with allogeneic, frozen, radiation-sterilised, corticocancellous blocks. The study included 26 grafting procedures with 7 procedures consisting in reconstruction of the alveolar ridge in the mandible and 19 in the maxilla. In all the cases the atrophied alveolar ridge was successfully reconstructed, which allowed placement of intraosseous implants in compliance with the initial treatment plan. After the treatment was completed the patients reported for follow-up annually. The average time of follow-up amounted to 39 months (28-50 months). None of the implants was lost during the follow-up period. There was one case of gingival recession causing aesthetics deterioration of the prosthetic restoration. In three cases the connector became unscrewed partially, which was corrected at the same visit. Frozen, radiation-sterilised, allogeneic bone blocks constitute good and durable bone-replacement material allowing effective and long-lasting reconstruction of the atrophied alveolar ridge to support durable, implant-based, prosthetic restoration.

Keywords: Allogeneic bone blocks; Allografts; Alveolar ridge augmentation; Pre-implantation procedure.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Atrophied alveolar ridge before augmentation
Fig. 2
Fig. 2
Bone block fixed to the ridge with two screws
Fig. 3
Fig. 3
Healed bone block graft
Fig. 4
Fig. 4
The tissue specimen from the site of implant embedment previously reconstructed with a biostatic bone graft. The graft restructuring can be confirmed by the occurrence of osteocytes in the lacunae. ×400 magnification, H&E staining
Fig. 5
Fig. 5
The bone block being partially exposed during the healing process
Fig. 6
Fig. 6
Aesthetics of prosthetic restoration 2.5 years after the treatment was completed
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. ANSI/AAMI/ISO 11137-1:2006a. Sterilization of health care products—radiation, part 1: requirements for development, validation and routine control of a sterilization process for medical devices. www.iso.org
    1. ANSI/AAMI/ISO 11137-2:2006b. Sterilization of health care products—radiation, part 2: establishing the sterilization dose, www.iso.org
    1. ANSI/AAMI/ISO 11137-3:2006c. Sterilization of health care products—radiation, part 3: guidance on dosimetric aspects, www.iso.org
    1. Bailey AJ. Effect of ionising radiation on connective tissue components. Int Rev Connect Tissue Res. 1968;4:233–281. doi: 10.1016/B978-1-4831-6754-1.50012-1. - DOI - PubMed
    1. Belser UC, Grütter L, Vailati F, Bornstein MM, Weber HP, Buser D. Outcome evaluation of early placed maxillary anterior single-tooth implants using objective esthetic criteria: a cross-sectional, retro-spective study in 45 patients with a 2- to 4-year follow-up using pink and white esthetic scores. J Periodontol. 2009;80:140–151. doi: 10.1902/jop.2009.080435. - DOI - PubMed

Publication types

MeSH terms

LinkOut - more resources