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Case Reports
. 1989 Dec;65(770):950-2.
doi: 10.1136/pgmj.65.770.950.

Life-threatening acute hyponatraemia induced by low dose cyclophosphamide and indomethacin

M J Webberley  1 , J A Murray
Affiliations
Case Reports

Life-threatening acute hyponatraemia induced by low dose cyclophosphamide and indomethacin

M J Webberley et al. Postgrad Med J. 1989 Dec.

Abstract

We report the case of a patient with multiple myeloma who developed acute life-threatening water intoxication following treatment with oral indomethacin and low dose intravenous cyclophosphamide. We describe a possible drug interaction between these two drugs and recommend that they should only be used together with caution.

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