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. 2015 Sep:105:165-8.
doi: 10.1016/j.fitote.2015.07.004. Epub 2015 Jul 9.

Velucarpins A-C, three new pterocarpans and their cytotoxicity from the roots of Dalbergia velutina

Sutin Kaennakam  1 , Pongpun Siripong  2 , Santi Tip-pyang  3
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Velucarpins A-C, three new pterocarpans and their cytotoxicity from the roots of Dalbergia velutina

Sutin Kaennakam et al. Fitoterapia. 2015 Sep.

Abstract

Three new pterocarpans, named velucarpins A-C (1-3), along with three known pterocarpans (4-6) were isolated from the roots of Dalbergia velutina. Their structures were determined by spectroscopic analysis. All isolated compounds were evaluated for their cytotoxicity against KB and HeLa cell lines. Compounds 3 and 5 showed good cytotoxicity against KB and HeLa cells with IC50 values of 8.22, 8.09 μM and 5.99, 8.69 μM, respectively.

Keywords: Cytotoxicity; Dalbergia velutina; Leguminosae; Pterocarpans; Velucarpins A–C.

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